The module will look at the role of molecular and cellular based diagnosis in a range of pathological conditions.
The history and development of cellular pathology will be introduced along with a review of increasing use of molecular based techniques to supplement existing diagnostic methods.
The student will be given an overview of processes involved in diagnosis using cell and tissue specimens. In particular, rationale of fixation will be discussed with particular reference to autolysis and putrefaction. The processing of samples from arrival at specimen reception to preparation of a stained, mounted specimen will be will be outlined. There will be reference to specific staining techniques including haematoxylin and eosin and selected special stains. The important role of immunohistochemistry in cellular pathology will be discussed with reference, for example, to identification of tumour type.
The role of cytology will be introduced, both in general terms and with particular reference to gynaecological cytology.
The role of genetic based techniques in pathology will be analysed and demonstrated, with the increasing importance of diagnostic techniques based on molecular biology, specifically in situ hybridisation, PCR and sequencing emphasised by combining technical presentations with examples of applications currently used in a pathology laboratory. Laboratory classes will be an integral part of this module and will typically involve problem based scenarios related as closely as possible to the clinical situation.
The module will be supported by external practitioners who will deliver lectures for selected parts of the module.
- This module will work to develop a number of the key “I am UWS” Graduate Attributes to make those who complete the module (e.g.)
Universal - Critical thinker, Analytical, Ethically-minded, Inquiring, Collaborative and Research Minded.
Work Ready - Knowledgeable, Digitally Literate, Problem-solver, effective communicator.
Successful - Autonomous, Innovative, Imaginative, Creative, Daring.
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